pubmed-article:17008930 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C0035696 | lld:lifeskim |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C1537987 | lld:lifeskim |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C0868955 | lld:lifeskim |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C1523987 | lld:lifeskim |
pubmed-article:17008930 | lifeskim:mentions | umls-concept:C1880371 | lld:lifeskim |
pubmed-article:17008930 | pubmed:issue | 11 | lld:pubmed |
pubmed-article:17008930 | pubmed:dateCreated | 2006-11-1 | lld:pubmed |
pubmed-article:17008930 | pubmed:abstractText | Trypanosomes use RNA editing to produce most functional mitochondrial messenger RNA. Precise insertion and deletion of hundreds of uridines is necessary to make full-length cytochrome c oxidase III (COXIII) mRNA. We show that COXIII mRNA can be alternatively edited by a mechanism using an alternative guide RNA to make a stable mRNA. This alternatively edited mRNA is translated to produce a unique protein that fractionates with mitochondrial membranes and colocalizes with mitochondrial proteins in situ. Alternative RNA editing represents a previously unknown mechanism generating protein diversity and, as such, represents an important function for RNA editing. | lld:pubmed |
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pubmed-article:17008930 | pubmed:language | eng | lld:pubmed |
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pubmed-article:17008930 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:17008930 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:17008930 | pubmed:month | Nov | lld:pubmed |
pubmed-article:17008930 | pubmed:issn | 1469-221X | lld:pubmed |
pubmed-article:17008930 | pubmed:author | pubmed-author:HajdukStephen... | lld:pubmed |
pubmed-article:17008930 | pubmed:author | pubmed-author:OchsenreiterT... | lld:pubmed |
pubmed-article:17008930 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:17008930 | pubmed:volume | 7 | lld:pubmed |
pubmed-article:17008930 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:17008930 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:17008930 | pubmed:pagination | 1128-33 | lld:pubmed |
pubmed-article:17008930 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:17008930 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:17008930 | pubmed:articleTitle | Alternative editing of cytochrome c oxidase III mRNA in trypanosome mitochondria generates protein diversity. | lld:pubmed |
pubmed-article:17008930 | pubmed:affiliation | Program in Global Infectious Diseases, Josephine Bay Paul Center, Marine Biological Laboratory, 7 MBL Street, Woods Hole, Massachusetts 02543, USA. | lld:pubmed |
pubmed-article:17008930 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:17008930 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:17008930 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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