| pubmed-article:17008425 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C0242767 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C0038250 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C0027215 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C2350292 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C0025201 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C1186763 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C1707937 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:17008425 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:17008425 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:17008425 | pubmed:dateCreated | 2007-2-7 | lld:pubmed |
| pubmed-article:17008425 | pubmed:abstractText | Corneal epithelial stem cells are known to be localized to the basal layer of the limbal epithelium, providing a model system for epithelial stem cell biology; however, the mechanisms regarding the maintenance of these stem cells in their specialized niche remain poorly understood. N-cadherin is a member of the classic cadherin family and has previously been demonstrated to be expressed by hematopoietic stem cells. In the present study, we demonstrate that N-cadherin is expressed by putative stem/progenitor cells, as well as melanocytes, in the human limbal epithelial stem cell niche. In addition, we demonstrate that upon in vitro culture using 3T3 feeder layers, loss of N-cadherin expression occurs with cell proliferation. These results indicate that N-cadherin may be a critical cell-to-cell adhesion molecule between corneal epithelial stem/progenitor cells and their corresponding niche cells in the limbal epithelium. | lld:pubmed |
| pubmed-article:17008425 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17008425 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17008425 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17008425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17008425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17008425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17008425 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17008425 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:17008425 | pubmed:issn | 1066-5099 | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:OkanoTeruoT | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:TanoYasuoY | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:YamatoMasayuk... | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:NishidaKohjiK | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:YangJosephJ | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:SumideTaizoT | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:SugiyamaHiroa... | lld:pubmed |
| pubmed-article:17008425 | pubmed:author | pubmed-author:HayashiRyuhei... | lld:pubmed |
| pubmed-article:17008425 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17008425 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:17008425 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17008425 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17008425 | pubmed:pagination | 289-96 | lld:pubmed |
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| pubmed-article:17008425 | pubmed:meshHeading | pubmed-meshheading:17008425... | lld:pubmed |
| pubmed-article:17008425 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17008425 | pubmed:articleTitle | N-Cadherin is expressed by putative stem/progenitor cells and melanocytes in the human limbal epithelial stem cell niche. | lld:pubmed |
| pubmed-article:17008425 | pubmed:affiliation | Department of Ophthalmology, Tohoku University School of Medicine, 1-1 Seiryomachi, Aoba-ku, Sendai 980-8574, Japan. | lld:pubmed |
| pubmed-article:17008425 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17008425 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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