Source:http://linkedlifedata.com/resource/pubmed/id/17004981
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2006-10-24
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pubmed:abstractText |
The aim of this study was to examine the influence of pre-pregnancy care and its effect on early glycaemic control and also the effect of glycaemic control in later pregnancy on risk of pre-eclampsia in women with type I diabetes. A prospective cohort study of 290 consecutive nonselected pregnancies in women with type I diabetes was performed from 1991 to 2002. We examined the relationship of monthly glycosylated haemoglobin (HbA1c) level, pre-pregnancy care, parity, diabetes duration, microvascular complications, maternal age, weight and smoking with risk of pre-eclampsia. Pre-eclampsia developed in 31/243 singleton births (12.8%). HbA1c level at 24 weeks was significantly increased in women with pre-eclampsia compared with women without pre-eclampsia (6.0 versus 5.6%, P= 0.017) and was, after nulliparity, the strongest independent predictor of increased risk (OR 1.65 for each 1% increase in HbA1c; P= 0.01). In contrast, there was no relationship between pre-pregnancy care or HbA1c level at booking and risk of pre-eclampsia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1470-0328
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1329-32
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pubmed:meshHeading |
pubmed-meshheading:17004981-Adult,
pubmed-meshheading:17004981-Analysis of Variance,
pubmed-meshheading:17004981-Blood Glucose,
pubmed-meshheading:17004981-Cohort Studies,
pubmed-meshheading:17004981-Diabetes Mellitus, Type 1,
pubmed-meshheading:17004981-Female,
pubmed-meshheading:17004981-Hemoglobin A, Glycosylated,
pubmed-meshheading:17004981-Humans,
pubmed-meshheading:17004981-Hypoglycemic Agents,
pubmed-meshheading:17004981-Pre-Eclampsia,
pubmed-meshheading:17004981-Preconception Care,
pubmed-meshheading:17004981-Pregnancy,
pubmed-meshheading:17004981-Pregnancy in Diabetics,
pubmed-meshheading:17004981-Prospective Studies,
pubmed-meshheading:17004981-Risk Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Glycaemic control throughout pregnancy and risk of pre-eclampsia in women with type I diabetes.
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pubmed:affiliation |
Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital NHS Trust, Norwich, UK. rosemary.temple@nnuh.nhs.uk
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pubmed:publicationType |
Journal Article
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