Linked Life Data

17003811

Source:http://linkedlifedata.com/resource/pubmed/id/17003811

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-12-14
pubmed:abstractText
Fistula use for dialysis is less frequent among obese than non-obese patients. This discrepancy may be due to a lower rate of fistula placement in obese patients, a higher primary failure rate (fistulas that are never usable for dialysis), or a higher secondary failure rate (fistulas that fail after being used successfully for dialysis). Using a prospective, computerized vascular access database, we identified all patients receiving a first fistula or graft at our institution during a 2-year period. The access outcomes were compared between obese (body mass index (BMI) >or=30 kg/m2) and non-obese (BMI<30 kg/m2) patients. Fistula placement was equally likely between obese and non-obese patients (47.4 vs 47.1%). The primary failure rate of fistulas was similar in both groups (46 vs 41%, P=0.45). Among those fistulas that were usable for dialysis, the secondary survival was worse in obese patients (hazard ratio 2.74; 95% confidence interval (CI), 1.48-7.90; P=0.004). Secondary fistula survival in obese vs non-obese patients was 68 vs 92% at 1 year, 59 vs 78% at 2 years, and 47 vs 70% at 3 years. On multiple variable survival analysis with age, sex, race, diabetes, coronary artery disease, peripheral vascular disease, fistula location, surgeon, and obesity in the model, obesity was the only significant factor predicting secondary fistula failure (hazards ratio 2.93; 95% CI, 1.44-5.93; P=0.004). In conclusion, long-term fistula survival is worse in obese than non-obese patients, owing to a higher secondary failure rate.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0085-2538
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-43
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Impact of obesity on arteriovenous fistula outcomes in dialysis patients.
pubmed:affiliation
Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural