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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1975-12-29
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pubmed:abstractText |
A case of mixed hepatoblastoma with osteoid elements was studied by light and electron microscopy. The ultrastructure of the epithelial elements showed a lack of differentiation and simple cytoplasmic organelles. However, an occasional cytoplasmic crystalloid structure were seen. The ultrastructure of the osteoid foci showed fibroblast-like cells capable of collagen formation, clearly distinguishable from the epithelial elements. These cells had neoplastic characteristics of nuclear pleomorphism and high nucleo-cytoplasmic ratio. These findings support the belief that hepatoblastoma arises from a multipotential blastema capable of both epithelial and mesenchymal differentiation, with the osteoid elements being an intrinsic neoplastic component of the tumor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1436-43
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:169988-Carcinoma, Hepatocellular,
pubmed-meshheading:169988-Cell Nucleus,
pubmed-meshheading:169988-Collagen,
pubmed-meshheading:169988-Cytoplasm,
pubmed-meshheading:169988-Epithelial Cells,
pubmed-meshheading:169988-Epithelium,
pubmed-meshheading:169988-Fibroblasts,
pubmed-meshheading:169988-Humans,
pubmed-meshheading:169988-Inclusion Bodies,
pubmed-meshheading:169988-Infant,
pubmed-meshheading:169988-Liver Neoplasms,
pubmed-meshheading:169988-Male
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pubmed:year |
1975
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pubmed:articleTitle |
An ultrastructural study of mixed hepatoblastoma with osteoid elements.
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pubmed:publicationType |
Journal Article,
Case Reports
|