Linked Life Data

16990185

Source:http://linkedlifedata.com/resource/pubmed/id/16990185

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-9-22
pubmed:abstractText
Immunoglobulins (Igs) against anti-human white blood cells are putative contributors to the development of transfusion-related adverse effects, particularly transfusion-related acute lung injury (TRALI). Studies of Igs that are considered to be implicated in transfusion-related adverse effects have mainly focused on immunoglobulin G (IgG) class antibodies (Abs). In the authors' previous in vitro study, the association of polymorphonuclear neutrophils (PMNs) and lung microvascular endothelial (LME) cells was up-regulated in the presence of normal human serum-derived IgMs, when F(ab')2 fragments of IgMs were specific to low-affinity Fc receptors (FcR) for IgG, namely, Fcgamma R III (CD16) and Fcgamma RII (CD32). In this study, the authors found that CD7 antigen notably expresses in LME cells and that it acts as an Fc receptor for IgM in LME cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1062-3329
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-92
pubmed:meshHeading
pubmed:articleTitle
Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M.
pubmed:affiliation
Research Section, Tokyo Metropolitan Red Cross Blood Center, Tokyo, Japan. mo-nishimura@tokyo.bc.jrc.or.jp
pubmed:publicationType
Journal Article