|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2006-9-21
|
|
pubmed:abstractText |
Previous studies have suggested that Optineurin (OPTN) sequence variants contribute to low-tension glaucoma (LTG) in ethnically homogeneous populations. The purpose of this study is to evaluate the prevalence of OPTN sequence variants in an ethnically diverse population of LTG patients from the United States, and to describe the phenotype of patients with OPTN sequence variants preferentially found in LTG patients.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1057-0829
|
|
pubmed:author |
pubmed-author:AugusteJosetteJ,
pubmed-author:DelbonoElizabethE,
pubmed-author:FlorJasonJ,
pubmed-author:GrahamFeliciaF,
pubmed-author:HainesJonathan LJL,
pubmed-author:HauserMichael AMA,
pubmed-author:Larocque-AbramsonKarenK,
pubmed-author:Pericak-VanceMargaret AMA,
pubmed-author:Rand AllinghamRR,
pubmed-author:SenaDayse FigueiredoDF,
pubmed-author:WalterJeffJ,
pubmed-author:WiggsJaney LJL
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
15
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
358-63
|
|
pubmed:dateRevised |
2007-12-3
|
|
pubmed:meshHeading |
pubmed-meshheading:16988596-Adult,
pubmed-meshheading:16988596-African Continental Ancestry Group,
pubmed-meshheading:16988596-Asian Americans,
pubmed-meshheading:16988596-Chromatography, High Pressure Liquid,
pubmed-meshheading:16988596-European Continental Ancestry Group,
pubmed-meshheading:16988596-Exons,
pubmed-meshheading:16988596-Female,
pubmed-meshheading:16988596-Genotype,
pubmed-meshheading:16988596-Glaucoma, Open-Angle,
pubmed-meshheading:16988596-Humans,
pubmed-meshheading:16988596-Male,
pubmed-meshheading:16988596-Middle Aged,
pubmed-meshheading:16988596-Ocular Hypertension,
pubmed-meshheading:16988596-Phenotype,
pubmed-meshheading:16988596-Polymerase Chain Reaction,
pubmed-meshheading:16988596-Polymorphism, Single Nucleotide,
pubmed-meshheading:16988596-Prevalence,
pubmed-meshheading:16988596-Sequence Analysis, DNA,
pubmed-meshheading:16988596-Transcription Factor TFIIIA,
pubmed-meshheading:16988596-United States
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States.
|
|
pubmed:affiliation |
Center for Human Genetics Duke School of Medicine, Harvard Medical School, Boston, MA 02114, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
