rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
|
pubmed:dateCreated |
2006-9-21
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pubmed:abstractText |
Previous studies have shown that broadly neutralizing antibodies (NAb) are more frequent in long-term non-progressors (LTNP) than in other HIV-1 infected patients, but nothing is known about the envelope regions targeted by these broadly NAb. We investigated whether the breadth of neutralizing activity of sera was associated with the presence of specific antibodies (2F5- and/or 4E10-like, b12-like or 2G12-like antibodies) directed against conserved epitopes known to be involved in broad neutralization.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0269-9370
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
3
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1923-30
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pubmed:meshHeading |
pubmed-meshheading:16988513-Antibody Specificity,
pubmed-meshheading:16988513-Antigen-Antibody Reactions,
pubmed-meshheading:16988513-Case-Control Studies,
pubmed-meshheading:16988513-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16988513-HIV Antibodies,
pubmed-meshheading:16988513-HIV Envelope Protein gp120,
pubmed-meshheading:16988513-HIV Envelope Protein gp41,
pubmed-meshheading:16988513-HIV Infections,
pubmed-meshheading:16988513-HIV Long-Term Survivors,
pubmed-meshheading:16988513-HIV-1,
pubmed-meshheading:16988513-Humans,
pubmed-meshheading:16988513-Immunodominant Epitopes,
pubmed-meshheading:16988513-Neutralization Tests,
pubmed-meshheading:16988513-Statistics, Nonparametric
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pubmed:year |
2006
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pubmed:articleTitle |
Antibodies to conserved epitopes of the HIV-1 envelope in sera from long-term non-progressors: prevalence and association with neutralizing activity.
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pubmed:affiliation |
Laboratoire de Virologie, Université François-Rabelais, INSERM ERI 19, 37044 Tours cedex, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|