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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2006-9-21
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pubmed:abstractText |
The -174 interleukin (IL)-6 gene polymorphism has been proposed as a risk factor for type 2 diabetes, but data are conflicting. Because white fat is a major source of IL-6 in resting individuals, we tested the hypothesis that BMI modifies the association among the IL-6 genotype, insulin resistance (IR) (measured using the homeostasis model), and risk of diabetes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1930-7381
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1454-61
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16988089-Blood Glucose,
pubmed-meshheading:16988089-Body Mass Index,
pubmed-meshheading:16988089-Fasting,
pubmed-meshheading:16988089-Female,
pubmed-meshheading:16988089-Genotype,
pubmed-meshheading:16988089-Homeostasis,
pubmed-meshheading:16988089-Humans,
pubmed-meshheading:16988089-Insulin,
pubmed-meshheading:16988089-Insulin Resistance,
pubmed-meshheading:16988089-Interleukin-6,
pubmed-meshheading:16988089-Male,
pubmed-meshheading:16988089-Middle Aged,
pubmed-meshheading:16988089-Models, Biological,
pubmed-meshheading:16988089-Odds Ratio,
pubmed-meshheading:16988089-Polymorphism, Genetic,
pubmed-meshheading:16988089-Promoter Regions, Genetic,
pubmed-meshheading:16988089-Sex Factors
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pubmed:year |
2006
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pubmed:articleTitle |
BMI modifies associations of IL-6 genotypes with insulin resistance: the Framingham Study.
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pubmed:affiliation |
Department of Genetics and Genomics, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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