|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2006-11-14
|
|
pubmed:abstractText |
Inherited erythermalgia (also termed "erythromelalgia"), characterized by episodic burning pain in the distal extremities evoked by warmth, has been causally linked with mutations of the Na(v)1.7 sodium channel, which is preferentially expressed in nociceptors. Thus far, Na(v)1.7 mutations within intracellular linker parts of the channel have been physiologically characterized.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1526-632X
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
14
|
|
pubmed:volume |
67
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1563-7
|
|
pubmed:meshHeading |
pubmed-meshheading:16988069-Action Potentials,
pubmed-meshheading:16988069-Cell Line,
pubmed-meshheading:16988069-Cell Membrane,
pubmed-meshheading:16988069-Erythromelalgia,
pubmed-meshheading:16988069-Extremities,
pubmed-meshheading:16988069-Ganglia, Spinal,
pubmed-meshheading:16988069-Humans,
pubmed-meshheading:16988069-Membrane Potentials,
pubmed-meshheading:16988069-Mutation,
pubmed-meshheading:16988069-Neural Conduction,
pubmed-meshheading:16988069-Neurons, Afferent,
pubmed-meshheading:16988069-Nociceptors,
pubmed-meshheading:16988069-Pain,
pubmed-meshheading:16988069-Patch-Clamp Techniques,
pubmed-meshheading:16988069-Protein Subunits,
pubmed-meshheading:16988069-Sodium Channels
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Inherited erythermalgia: limb pain from an S4 charge-neutral Na channelopathy.
|
|
pubmed:affiliation |
Department of Neurology, Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT 06510, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|
