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16987662
Source:
http://linkedlifedata.com/resource/pubmed/id/16987662
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0005029
,
umls-concept:C0205549
,
umls-concept:C0220781
,
umls-concept:C0243077
,
umls-concept:C0268563
,
umls-concept:C1420220
,
umls-concept:C1441547
,
umls-concept:C1611588
,
umls-concept:C1883254
pubmed:issue
23
pubmed:dateCreated
2006-11-10
pubmed:abstractText
This Letter describes the synthesis and SAR, developed through an iterative analog library approach, of potent and selective non-sarcosine-derived GlyT1 inhibitors.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Amides
,
http://linkedlifedata.com/resource/pubmed/chemical/Benzamides
,
http://linkedlifedata.com/resource/pubmed/chemical/Glycine Plasma Membrane Transport...
,
http://linkedlifedata.com/resource/pubmed/chemical/Morpholines
,
http://linkedlifedata.com/resource/pubmed/chemical/Piperidines
,
http://linkedlifedata.com/resource/pubmed/chemical/piperidine
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0960-894X
pubmed:author
pubmed-author:HartmanGeorge DGD
,
pubmed-author:JacobsonMarlene AMA
,
pubmed-author:LemaireWeiW
,
pubmed-author:LindsleyCraig WCW
,
pubmed-author:O'BrienJulie AJA
,
pubmed-author:PettiboneDoug JDJ
,
pubmed-author:SmithSheriS
,
pubmed-author:SurCyrilleC
,
pubmed-author:TillerPhilip RPR
,
pubmed-author:WilliamsDavid LDLJr
,
pubmed-author:WolkenbergScott ESE
,
pubmed-author:ZhaoZhijianZ
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5968-72
pubmed:meshHeading
pubmed-meshheading:16987662-Amides
,
pubmed-meshheading:16987662-Animals
,
pubmed-meshheading:16987662-Benzamides
,
pubmed-meshheading:16987662-Glycine Plasma Membrane Transport Proteins
,
pubmed-meshheading:16987662-Humans
,
pubmed-meshheading:16987662-Methylation
,
pubmed-meshheading:16987662-Mice
,
pubmed-meshheading:16987662-Molecular Structure
,
pubmed-meshheading:16987662-Morpholines
,
pubmed-meshheading:16987662-Piperidines
,
pubmed-meshheading:16987662-Rats
,
pubmed-meshheading:16987662-Structure-Activity Relationship
pubmed:year
2006
pubmed:articleTitle
Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.
pubmed:affiliation
Department of Medicinal Chemistry, Merck and Co., Inc., PO Box 4, West Point, PA 19486, USA. zhijian_zhao@merck.com <zhijian_zhao@merck.com>
pubmed:publicationType
Journal Article