Source:http://linkedlifedata.com/resource/pubmed/id/16987659
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
23
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pubmed:dateCreated |
2006-11-10
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pubmed:abstractText |
Various compounds were evaluated for ability to inhibit the formation of the abnormal protease-resistant form of prion protein (PrP-res) in two cell lines infected with different prion strains. Examination of the structure-activity relationships indicated that compounds with copper-selective chelating ability and whose copper complexes have high SOD-like activity are candidates for anti-prion drug.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5982-7
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pubmed:meshHeading |
pubmed-meshheading:16987659-Cell Line,
pubmed-meshheading:16987659-Chelating Agents,
pubmed-meshheading:16987659-Copper,
pubmed-meshheading:16987659-Molecular Structure,
pubmed-meshheading:16987659-Prions,
pubmed-meshheading:16987659-Spectrum Analysis,
pubmed-meshheading:16987659-Structure-Activity Relationship,
pubmed-meshheading:16987659-Superoxide Dismutase
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pubmed:year |
2006
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pubmed:articleTitle |
Metal complexes with superoxide dismutase-like activity as candidates for anti-prion drug.
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pubmed:affiliation |
Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan. t-fukuu@ps.hirokoku-u.ac.jp <t-fukuu@ps.hirokoku-u.ac.jp>
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pubmed:publicationType |
Journal Article
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