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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-9-20
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pubmed:abstractText |
We studied the neurotropic effects of ACTH(4-10) analog semax against the background of dopaminergic receptors blockade with haloperidol. Intranasal administration of semax (0.05, 0.2, and 0.6 mg/kg) produced virtually no effect on disturbances of orientation and exploratory reactions and motor activity caused by intraperitoneal injection of 0.2 mg/kg haloperidol. By contrast, preliminary administration of 0.05 mg/kg semax prevented haloperidol-induced disturbances in active avoidance conditioning.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0007-4888
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
170-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16984088-Administration, Intranasal,
pubmed-meshheading:16984088-Adrenocorticotropic Hormone,
pubmed-meshheading:16984088-Animals,
pubmed-meshheading:16984088-Avoidance Learning,
pubmed-meshheading:16984088-Dopamine Antagonists,
pubmed-meshheading:16984088-Drug Interactions,
pubmed-meshheading:16984088-Exploratory Behavior,
pubmed-meshheading:16984088-Haloperidol,
pubmed-meshheading:16984088-Injections, Intraperitoneal,
pubmed-meshheading:16984088-Motor Activity,
pubmed-meshheading:16984088-Neuroprotective Agents,
pubmed-meshheading:16984088-Orientation,
pubmed-meshheading:16984088-Peptide Fragments,
pubmed-meshheading:16984088-Rats,
pubmed-meshheading:16984088-Receptors, Dopamine
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pubmed:year |
2006
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pubmed:articleTitle |
Effects of semax against the background of dopaminergic receptor blockade with haloperidol.
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pubmed:affiliation |
Department of Human and Animal Physiology, Biological Faculty, M V Lomonosov Moscow State University.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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