rdf:type |
|
lifeskim:mentions |
umls-concept:C0006826,
umls-concept:C0008044,
umls-concept:C0008976,
umls-concept:C0019994,
umls-concept:C0036525,
umls-concept:C0041740,
umls-concept:C0205179,
umls-concept:C0205390,
umls-concept:C0282460,
umls-concept:C0879272,
umls-concept:C1176309,
umls-concept:C1513822,
umls-concept:C1522484,
umls-concept:C1880171
|
pubmed:issue |
2
|
pubmed:dateCreated |
2006-12-22
|
pubmed:abstractText |
Based on evidence of activity in epithelial tumors in preclinical and Phase I studies, its novel mechanism of action, and its tolerability we undertook a study of bortezomib [PS-341], a reversible proteasome inhibitor, for patients with advanced or metastatic urothelial cancer.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0167-6997
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
181-5
|
pubmed:dateRevised |
2007-12-3
|
pubmed:meshHeading |
pubmed-meshheading:16983508-Aged,
pubmed-meshheading:16983508-Aged, 80 and over,
pubmed-meshheading:16983508-Antineoplastic Agents,
pubmed-meshheading:16983508-Boronic Acids,
pubmed-meshheading:16983508-Disease Progression,
pubmed-meshheading:16983508-Drug Resistance, Neoplasm,
pubmed-meshheading:16983508-Female,
pubmed-meshheading:16983508-Humans,
pubmed-meshheading:16983508-Infusions, Intravenous,
pubmed-meshheading:16983508-Male,
pubmed-meshheading:16983508-Middle Aged,
pubmed-meshheading:16983508-Neoplasm Metastasis,
pubmed-meshheading:16983508-Pyrazines,
pubmed-meshheading:16983508-Survival Analysis,
pubmed-meshheading:16983508-Urologic Neoplasms,
pubmed-meshheading:16983508-Urothelium
|
pubmed:year |
2007
|
pubmed:articleTitle |
A phase II study of PS-341 (Bortezomib) in advanced or metastatic urothelial cancer. A trial of the Princess Margaret Hospital and University of Chicago phase II consortia.
|
pubmed:affiliation |
Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
|
pubmed:publicationType |
Journal Article,
Multicenter Study,
Clinical Trial, Phase II,
Research Support, N.I.H., Extramural
|