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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-9-19
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pubmed:abstractText |
The Mannan-binding lectin (MBL) pathway involves recognition of fungal surfaces by MBL and cleavage of C2 and C4 by MBL-associated serine protease (namely, MASP-2). Recent data show that MBL pathway deficiency might result not only from polymorphisms of the MBL2 gene but also of MASP2. The aim of the study was to assess whether polymorphisms of these genes are associated with invasive fungal infections (IFIs) following allogeneic stem cell transplantation (allo-SCT).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0301-472X
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pubmed:author |
pubmed-author:CarrerasEnricE,
pubmed-author:Fernández-AvilésFrancescF,
pubmed-author:GayaAnnaA,
pubmed-author:GranellMiquelM,
pubmed-author:LozanoFranciscoF,
pubmed-author:MartínezCarmenC,
pubmed-author:MensaJosepJ,
pubmed-author:MontserratEmiliE,
pubmed-author:NavarroAlfonsA,
pubmed-author:OrtegaMarM,
pubmed-author:RonceroJosep M AJM,
pubmed-author:RoviraMontserratM,
pubmed-author:RozmanCirilC,
pubmed-author:SuarezBelénB,
pubmed-author:Urbano-IspizuaAlvaroA,
pubmed-author:UriburuCarlaC,
pubmed-author:VivesJordiJ
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1435-41
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16982337-Acute Disease,
pubmed-meshheading:16982337-Adult,
pubmed-meshheading:16982337-Complement C2,
pubmed-meshheading:16982337-Complement C4,
pubmed-meshheading:16982337-Complement Pathway, Mannose-Binding Lectin,
pubmed-meshheading:16982337-DNA Mutational Analysis,
pubmed-meshheading:16982337-Exons,
pubmed-meshheading:16982337-Female,
pubmed-meshheading:16982337-Genetic Predisposition to Disease,
pubmed-meshheading:16982337-Genotype,
pubmed-meshheading:16982337-Graft vs Host Disease,
pubmed-meshheading:16982337-Hematologic Neoplasms,
pubmed-meshheading:16982337-Humans,
pubmed-meshheading:16982337-Male,
pubmed-meshheading:16982337-Mannose-Binding Lectin,
pubmed-meshheading:16982337-Mannose-Binding Protein-Associated Serine Proteases,
pubmed-meshheading:16982337-Middle Aged,
pubmed-meshheading:16982337-Mycoses,
pubmed-meshheading:16982337-Polymorphism, Genetic,
pubmed-meshheading:16982337-Predictive Value of Tests,
pubmed-meshheading:16982337-Prognosis,
pubmed-meshheading:16982337-Promoter Regions, Genetic,
pubmed-meshheading:16982337-Stem Cell Transplantation,
pubmed-meshheading:16982337-Tissue Donors,
pubmed-meshheading:16982337-Transplantation, Homologous
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pubmed:year |
2006
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pubmed:articleTitle |
Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation.
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pubmed:affiliation |
Departments of Hematology, Hospital Clínic of Barcelona, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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