|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0021853,
umls-concept:C0039194,
umls-concept:C0085358,
umls-concept:C0086418,
umls-concept:C0108789,
umls-concept:C0123745,
umls-concept:C0175630,
umls-concept:C0205251,
umls-concept:C0439165,
umls-concept:C0856825,
umls-concept:C1332717,
umls-concept:C1413244,
umls-concept:C1705576,
umls-concept:C1706438,
umls-concept:C2698600,
umls-concept:C2745955
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2006-9-19
|
|
pubmed:abstractText |
Effector phase of acute graft-versus-host disease (a-GVHD) is mainly mediated by donor-derived, anti-host cytotoxic T cells. T-cell homing into gut-associated lymphoid tissues is ascribed to the alpha4beta7 integrin. We reasoned that development of intestinal a-GVHD might be triggered by recruitment in the intestinal mucosa of circulating, alloreactive, alpha4beta7(+) donor T cells. Therefore, we evaluated the correlation existing between circulating beta7(+) T-lymphocyte subsets early after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and occurrence of a-GVHD.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0301-472X
|
|
pubmed:author |
pubmed-author:AmendolaGiovanniG,
pubmed-author:AvanziniM AntoniettaMA,
pubmed-author:BernardoMaria EsterME,
pubmed-author:GiebelSebastianS,
pubmed-author:LocatelliFrancoF,
pubmed-author:LongoStefaniaS,
pubmed-author:MaccarioRitaR,
pubmed-author:MarconiMassimoM,
pubmed-author:MontagnaDanielaD,
pubmed-author:PagliaraDariaD,
pubmed-author:SantosConceiçao DosCD
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
34
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1429-34
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16982336-Acute Disease,
pubmed-meshheading:16982336-Adolescent,
pubmed-meshheading:16982336-Adult,
pubmed-meshheading:16982336-Biological Markers,
pubmed-meshheading:16982336-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16982336-Child,
pubmed-meshheading:16982336-Child, Preschool,
pubmed-meshheading:16982336-Female,
pubmed-meshheading:16982336-Graft vs Host Disease,
pubmed-meshheading:16982336-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:16982336-Humans,
pubmed-meshheading:16982336-Infant,
pubmed-meshheading:16982336-Integrin beta Chains,
pubmed-meshheading:16982336-Integrins,
pubmed-meshheading:16982336-Intestinal Diseases,
pubmed-meshheading:16982336-Intestinal Mucosa,
pubmed-meshheading:16982336-Lymphocyte Count,
pubmed-meshheading:16982336-Male,
pubmed-meshheading:16982336-Neoplasms,
pubmed-meshheading:16982336-Transplantation, Homologous
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Low percentages of circulating CD8(+)/CD45RA(+) human T lymphocytes expressing beta7 integrin correlate with the occurrence of intestinal acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
|
|
pubmed:affiliation |
Pediatric Hematology-Oncology and Laboratory of Transplant Immunology, IRCCS Policlinico San Matteo-Pavia, University of Pavia, Pavia, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
