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rdf:type |
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lifeskim:mentions |
umls-concept:C0008838,
umls-concept:C0017262,
umls-concept:C0038952,
umls-concept:C0045093,
umls-concept:C0205179,
umls-concept:C0332293,
umls-concept:C0681890,
umls-concept:C0684249,
umls-concept:C1333355,
umls-concept:C1335648,
umls-concept:C1414313
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pubmed:issue |
12
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pubmed:dateCreated |
2006-12-7
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pubmed:abstractText |
Pivotal studies indicate a role of excision repair cross-complementation 1 (ERCC1) gene and ribonucleotide reductase M1 (RRM1) gene in conferring a differential sensitivity to cytotoxic chemotherapy and epidermal growth factor receptor (EGFR) gene has been recently extensively investigated in non-small-cell lung cancer (NSCLC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cisplatin,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxycytidine,
http://linkedlifedata.com/resource/pubmed/chemical/ERCC1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Endonucleases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RRM1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/gemcitabine
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0923-7534
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pubmed:author |
pubmed-author:CalogeroRR,
pubmed-author:CambieriAA,
pubmed-author:CeppiPP,
pubmed-author:DanenbergK DKD,
pubmed-author:DanenbergP VPV,
pubmed-author:NovelloSS,
pubmed-author:PapottiMM,
pubmed-author:RappFF,
pubmed-author:SaviozziSS,
pubmed-author:ScagliottiG VGV,
pubmed-author:SelvaggiGG,
pubmed-author:VolanteMM
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1818-25
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16980606-Adult,
pubmed-meshheading:16980606-Aged,
pubmed-meshheading:16980606-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16980606-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:16980606-Cisplatin,
pubmed-meshheading:16980606-DNA-Binding Proteins,
pubmed-meshheading:16980606-Deoxycytidine,
pubmed-meshheading:16980606-Endonucleases,
pubmed-meshheading:16980606-Female,
pubmed-meshheading:16980606-Gene Expression,
pubmed-meshheading:16980606-Humans,
pubmed-meshheading:16980606-Lung Neoplasms,
pubmed-meshheading:16980606-Male,
pubmed-meshheading:16980606-Middle Aged,
pubmed-meshheading:16980606-Prognosis,
pubmed-meshheading:16980606-RNA, Messenger,
pubmed-meshheading:16980606-Receptor, Epidermal Growth Factor,
pubmed-meshheading:16980606-Retrospective Studies,
pubmed-meshheading:16980606-Survival Analysis,
pubmed-meshheading:16980606-Tumor Suppressor Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine.
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pubmed:affiliation |
Thoracic Oncology Unit, Orbassano, Torino, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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