rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2007-1-11
|
pubmed:abstractText |
Levonorgestrel (LNG) consistently prevents follicular rupture only when it is given before the onset of the ovulatory stimulus. As locally synthesized prostaglandin (PG) plays a crucial role in follicular rupture and cyclooxygenase-2 (cox-2) catalyses the final step of PG synthesis, we reasoned that adding a cox-2 inhibitor to LNG would prevent follicular rupture even after the ovulatory process had been triggered by the gonadotrophin surge.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0268-1161
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
434-9
|
pubmed:meshHeading |
pubmed-meshheading:16980507-Adolescent,
pubmed-meshheading:16980507-Adult,
pubmed-meshheading:16980507-Anovulation,
pubmed-meshheading:16980507-Chile,
pubmed-meshheading:16980507-Contraceptives, Postcoital, Synthetic,
pubmed-meshheading:16980507-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:16980507-Dominican Republic,
pubmed-meshheading:16980507-Female,
pubmed-meshheading:16980507-Humans,
pubmed-meshheading:16980507-Levonorgestrel,
pubmed-meshheading:16980507-Ovarian Follicle,
pubmed-meshheading:16980507-Thiazines,
pubmed-meshheading:16980507-Thiazoles
|
pubmed:year |
2007
|
pubmed:articleTitle |
Does meloxicam increase the incidence of anovulation induced by single administration of levonorgestrel in emergency contraception? A pilot study.
|
pubmed:affiliation |
Instituto Chileno de Medicina Reproductiva (ICMER), Santiago, Chile. rmassai@icmer.org
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|