| pubmed-article:16973328 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0003402 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0227843 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0012087 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0042874 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:16973328 | lifeskim:mentions | umls-concept:C1883709 | lld:lifeskim |
| pubmed-article:16973328 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:16973328 | pubmed:dateCreated | 2006-10-18 | lld:pubmed |
| pubmed-article:16973328 | pubmed:abstractText | We aimed to investigate the effect of subchronic administration of dichlorvos (DDVP) on endometrium and to evaluate ameliorating effects of a combination of Vitamins E and C against DDVP toxicity in the rat. Three groups of rats were used in the experiment. The first group was treated with 4 mg/kg DDVP; the second group was treated with 4 mg/kg body weight DDVP plus Vitamins E and C (DDVP+Vit); the third group was given only corn oil (control). DDVP and DDVP+Vit groups were given DDVP by gavage 5 days a week for 4 weeks at a dose level of 4 mg/kg day by using corn oil as the vechicle. Vitamins E and C were injected at doses of 50 mg/kg i.m. and 20 mg/kg body weight i.p. Histopathological and immunohistochemical examinations for caspase-3 and caspase-9 were accomplished in the endometrium. The level of malondialdehyde (MDA) increased significantly in the DDVP group compared with the control group (p<0.05). MDA significantly decreased in the DDVP+Vit group compared with the DDVP group (p<0.05). Administration of Vitamins E and C along with DDVP significantly reduced the histopathological changes and the extent of apoptosis. In conclusion, subchronic DDVP administration caused endometrial damage and that treatment with a combination of Vitamins E and C reduced endometrial damage caused by DDVP. | lld:pubmed |
| pubmed-article:16973328 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16973328 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16973328 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16973328 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16973328 | pubmed:issn | 0890-6238 | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:AltuntasIrfan... | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:OralBahaB | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:OzgunerMeltem... | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:MunganTamerT | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:DemirinHilmiH | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:GuneyMehmetM | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:GiraySeren... | lld:pubmed |
| pubmed-article:16973328 | pubmed:author | pubmed-author:TakeGulnurG | lld:pubmed |
| pubmed-article:16973328 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16973328 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:16973328 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16973328 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16973328 | pubmed:pagination | 783-90 | lld:pubmed |
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| pubmed-article:16973328 | pubmed:meshHeading | pubmed-meshheading:16973328... | lld:pubmed |
| pubmed-article:16973328 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16973328 | pubmed:articleTitle | Endometrial damage and apoptosis in rats induced by dichlorvos and ameliorating effect of antioxidant vitamins E and C. | lld:pubmed |
| pubmed-article:16973328 | pubmed:affiliation | Department of Obstetrics and Gynecology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey. | lld:pubmed |
| pubmed-article:16973328 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16973328 | lld:pubmed |
