Source:http://linkedlifedata.com/resource/pubmed/id/16971564
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
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| pubmed:dateCreated |
2006-9-14
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| pubmed:abstractText |
A total of 90 weaned female pigs (Duroc x Landrace x Yorkshire) were used in a 15-d growth experiment to investigate the effect of lactoferrin on growth performance, intestinal morphology, and expression of PR-39 and protegrin-1 genes. The pigs were allocated on the basis of BW and litter to 3 dietary treatments in a randomized complete block design. There were 3 replicate pens per treatment, and the pigs were grouped with 10 pigs per pen. The dietary treatments were (1) basal diet; (2) basal diet + 20 mg of flavomycin/kg + 110 mg of aureomycin/kg; (3) basal diet + 1.0 g of lactoferrin/kg. Six pigs, randomly selected from each treatment (2 piglets/pen) were slaughtered for intestinal morphology and expression of PR-39 and protegrin-1 genes at the end of the experiment. Supplementation with lactoferrin improved growth performance; it increased ADG by 41.80% (P < 0.01) and efficiency of gain (G:F) by 17.20% (P < 0.05). Intestinal villus height was increased by 15.30% (P < 0.05), and crypt depth was decreased by 9.60% (P < 0.05). Supplemental lactoferrin increased the relative abundance of mRNA for PR-39 and protegrin-1 by 143% (P < 0.01) and 217% (P < 0.01), respectively. The use of lactoferrin as an additive to improve nonspecific immunity and strengthen host defenses would be good a method of defending weaned pigs from infections and weanling stress.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Antimicrobial Cationic Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Bambermycins,
http://linkedlifedata.com/resource/pubmed/chemical/Chlortetracycline,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Lactoferrin,
http://linkedlifedata.com/resource/pubmed/chemical/PR 39,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/protegrin-1
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| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
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| pubmed:issn |
1525-3163
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
84
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
2636-41
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| pubmed:dateRevised |
2011-11-17
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| pubmed:meshHeading |
pubmed-meshheading:16971564-Actins,
pubmed-meshheading:16971564-Animal Feed,
pubmed-meshheading:16971564-Animals,
pubmed-meshheading:16971564-Anti-Bacterial Agents,
pubmed-meshheading:16971564-Antimicrobial Cationic Peptides,
pubmed-meshheading:16971564-Bambermycins,
pubmed-meshheading:16971564-Bone Marrow,
pubmed-meshheading:16971564-Chlortetracycline,
pubmed-meshheading:16971564-DNA Primers,
pubmed-meshheading:16971564-Dietary Supplements,
pubmed-meshheading:16971564-Female,
pubmed-meshheading:16971564-Gene Expression,
pubmed-meshheading:16971564-Growth,
pubmed-meshheading:16971564-Intestine, Small,
pubmed-meshheading:16971564-Lactoferrin,
pubmed-meshheading:16971564-Proteins,
pubmed-meshheading:16971564-Random Allocation,
pubmed-meshheading:16971564-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16971564-Swine
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| pubmed:year |
2006
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| pubmed:articleTitle |
Effect of lactoferrin on the growth performance, intestinal morphology, and expression of PR-39 and protegrin-1 genes in weaned piglets.
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| pubmed:affiliation |
Institute of Feed Science, Zhejiang University, The Key Laboratory of Molecular Animal Nutrition, Ministry of Education, No. 164 Qiutao North Road, Hangzhou 310029, P. R. China. yzwang@zju.edu.cn
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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