Source:http://linkedlifedata.com/resource/pubmed/id/16971357
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2006-9-14
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pubmed:abstractText |
This is a case report of a 56-year-old man with plasma cell dyscrasia who presented with proximal tubulopathy manifested as kappa light-chain crystal deposition in the proximal convoluted tubular cells. This was associated with mild cellular damage. The crystals were seen as negative images with the hematoxylin-eosin and periodic acid-Schiff (PAS) stains. They were identified as kappa light-chains by immunofluorescent imaging and confirmed by immunoelectron microscopy. Ultrastructurally, the crystals appear to be located within lysosomes. No deposits of light-chains were seen elsewhere in the kidney biopsy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1521-0758
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
315-9
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pubmed:dateRevised |
2009-6-26
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pubmed:meshHeading |
pubmed-meshheading:16971357-Crystallization,
pubmed-meshheading:16971357-Fluorescent Antibody Technique,
pubmed-meshheading:16971357-Humans,
pubmed-meshheading:16971357-Immunoglobulin kappa-Chains,
pubmed-meshheading:16971357-Kidney Tubules, Proximal,
pubmed-meshheading:16971357-Male,
pubmed-meshheading:16971357-Microscopy, Electron,
pubmed-meshheading:16971357-Microscopy, Immunoelectron,
pubmed-meshheading:16971357-Middle Aged,
pubmed-meshheading:16971357-Paraproteinemias
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pubmed:articleTitle |
Plasma cell dyscrasia with kappa light-chain crystals in proximal tubular cells: a histological, immunofluorescent, and ultrastructural study.
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pubmed:affiliation |
Department of Pathology, New York University Medical Center, New York, New York, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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