Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2006-9-13
pubmed:abstractText
We experienced a case of multi-drug resistant recurrent breast cancer with multiple bone metastases achieving a significant improvement by TS-1 and trastuzumab. The prior treatments including taxane or vinorelbine and trastuzumab were changed in the regimen to TS-1 and trastuzumab because of the progressive disease. TS-1 was administered orally at 100 mg/day everyday for 2 weeks, followed by a 1-week rest interval as 1 cycle, and trastuzumab was injected at 2 mg/kg/week for 4 weeks, followed by a 1-week rest interval as 1 cycle. After 3 cycles of the treatment, the level of tumor markers and tumor sizes of bone metastases became reduced. In conclusion, the combination treatment of TS-1 and trastuzumab is thought to be effective for multi-drug resistant recurrent breast cancer.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0385-0684
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1305-8
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:16969030-Antibodies, Monoclonal, pubmed-meshheading:16969030-Antibodies, Monoclonal, Humanized, pubmed-meshheading:16969030-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:16969030-Bone Neoplasms, pubmed-meshheading:16969030-Breast Neoplasms, pubmed-meshheading:16969030-Carcinoma, Ductal, Breast, pubmed-meshheading:16969030-Drug Administration Schedule, pubmed-meshheading:16969030-Drug Combinations, pubmed-meshheading:16969030-Female, pubmed-meshheading:16969030-Humans, pubmed-meshheading:16969030-Lymph Nodes, pubmed-meshheading:16969030-Lymphatic Metastasis, pubmed-meshheading:16969030-Mastectomy, Segmental, pubmed-meshheading:16969030-Middle Aged, pubmed-meshheading:16969030-Oxonic Acid, pubmed-meshheading:16969030-Receptor, erbB-2, pubmed-meshheading:16969030-Tegafur
pubmed:year
2006
pubmed:articleTitle
[A case of multi-drug resistant recurrent breast cancer with multiple bone metastasis responding to TS-1 and trastuzumab].
pubmed:affiliation
Dept. of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine.
pubmed:publicationType
Journal Article, English Abstract, Case Reports