rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-9-13
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pubmed:abstractText |
We experienced a case of multi-drug resistant recurrent breast cancer with multiple bone metastases achieving a significant improvement by TS-1 and trastuzumab. The prior treatments including taxane or vinorelbine and trastuzumab were changed in the regimen to TS-1 and trastuzumab because of the progressive disease. TS-1 was administered orally at 100 mg/day everyday for 2 weeks, followed by a 1-week rest interval as 1 cycle, and trastuzumab was injected at 2 mg/kg/week for 4 weeks, followed by a 1-week rest interval as 1 cycle. After 3 cycles of the treatment, the level of tumor markers and tumor sizes of bone metastases became reduced. In conclusion, the combination treatment of TS-1 and trastuzumab is thought to be effective for multi-drug resistant recurrent breast cancer.
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pubmed:language |
jpn
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Oxonic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/S 1 (combination),
http://linkedlifedata.com/resource/pubmed/chemical/Tegafur,
http://linkedlifedata.com/resource/pubmed/chemical/trastuzumab
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0385-0684
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1305-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16969030-Antibodies, Monoclonal,
pubmed-meshheading:16969030-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:16969030-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16969030-Bone Neoplasms,
pubmed-meshheading:16969030-Breast Neoplasms,
pubmed-meshheading:16969030-Carcinoma, Ductal, Breast,
pubmed-meshheading:16969030-Drug Administration Schedule,
pubmed-meshheading:16969030-Drug Combinations,
pubmed-meshheading:16969030-Female,
pubmed-meshheading:16969030-Humans,
pubmed-meshheading:16969030-Lymph Nodes,
pubmed-meshheading:16969030-Lymphatic Metastasis,
pubmed-meshheading:16969030-Mastectomy, Segmental,
pubmed-meshheading:16969030-Middle Aged,
pubmed-meshheading:16969030-Oxonic Acid,
pubmed-meshheading:16969030-Receptor, erbB-2,
pubmed-meshheading:16969030-Tegafur
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pubmed:year |
2006
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pubmed:articleTitle |
[A case of multi-drug resistant recurrent breast cancer with multiple bone metastasis responding to TS-1 and trastuzumab].
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pubmed:affiliation |
Dept. of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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