Linked Life Data

1696767

Source:http://linkedlifedata.com/resource/pubmed/id/1696767

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-9-20
pubmed:abstractText
Preparations of anti-I--J alloantisera with higher activity were obtained by a new method, based on induction of expression of the I--J determinant in donor suppressor cells, immunization of mice with such cells, and subsequent elimination of contaminating anti-idiotypic antibodies from antisera by their adsorption on the cells of the recipient murine strain sharing induced idiotype with the donor cells. After adsorption anti-I--J activity remained unchanged. The antisera thus obtained were found active in the standard cytotoxic assay (working dilution greater than or equal to 1:20). The injection of anti-I--Jk antiserum to CBA mice prolonged the survival time of the animals and increased the parameters of the cell-mediated immunity after infection with Mycobacterium tuberculosis virulent strain H37Rv.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0372-9311
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
76-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[New alloantisera to antigenic determinant I--J, their specificity and effect on the course of tuberculous infection in mice].
pubmed:publicationType
Journal Article, English Abstract