| pubmed-article:1696718 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C0003402 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C0014834 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C0206522 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C0450442 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C2348867 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C1880266 | lld:lifeskim |
| pubmed-article:1696718 | lifeskim:mentions | umls-concept:C1883676 | lld:lifeskim |
| pubmed-article:1696718 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:1696718 | pubmed:dateCreated | 1990-9-20 | lld:pubmed |
| pubmed-article:1696718 | pubmed:abstractText | Escherichia coli responds to superoxide-generating agents by inducing approximately 40 proteins. We have identified a genetic locus, soxR (superoxide response), that positively regulates 9 of these proteins during superoxide stress. Induction under soxR control is at the transcriptional level, as shown with lac fusions to five paraquat-inducible promoters. Members of the soxR regulon include at least three proteins with demonstrable antioxidant roles: Mn-containing superoxide dismutase (which destroys superoxide radicals), endonuclease IV (which repairs radical-induced damages in DNA), and glucose-6-phosphate dehydrogenase (which produces NADPH). Induction of the soxR regulon also leads to diminished levels of the major outer membrane protein OmpF and alteration of the small-subunit ribosomal protein S6. These latter changes confer resistance to a variety of antibiotics. The soxR regulon may thus operate as an inducible defense against xenobiotics in general. | lld:pubmed |
| pubmed-article:1696718 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1696718 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1696718 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1696718 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1696718 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:1696718 | pubmed:author | pubmed-author:JosephyP DPD | lld:pubmed |
| pubmed-article:1696718 | pubmed:author | pubmed-author:DempleBB | lld:pubmed |
| pubmed-article:1696718 | pubmed:author | pubmed-author:ChouJ HJH | lld:pubmed |
| pubmed-article:1696718 | pubmed:author | pubmed-author:GreenbergJ... | lld:pubmed |
| pubmed-article:1696718 | pubmed:author | pubmed-author:MonachPP | lld:pubmed |
| pubmed-article:1696718 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1696718 | pubmed:volume | 87 | lld:pubmed |
| pubmed-article:1696718 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1696718 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1696718 | pubmed:pagination | 6181-5 | lld:pubmed |
| pubmed-article:1696718 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:meshHeading | pubmed-meshheading:1696718-... | lld:pubmed |
| pubmed-article:1696718 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1696718 | pubmed:articleTitle | Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli. | lld:pubmed |
