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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-9-11
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pubmed:abstractText |
The extreme sib-pair approach has been shown to be a powerful strategy to identify susceptibility loci linked to quantitative traits. The body mass index is the usually assessed trait in genetic studies on human obesity. Environmental factors clearly play an important role for this trait. We hypothesized that the low weight of most sibs who were seemingly discordant to the obese index proband was influenced by other environmental and/or genetic factors like restrained eating or psychiatric disorders.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0026-1270
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
419-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16964359-Adolescent,
pubmed-meshheading:16964359-Body Mass Index,
pubmed-meshheading:16964359-Child,
pubmed-meshheading:16964359-Confounding Factors (Epidemiology),
pubmed-meshheading:16964359-Feeding Behavior,
pubmed-meshheading:16964359-Female,
pubmed-meshheading:16964359-Gene Frequency,
pubmed-meshheading:16964359-Genotype,
pubmed-meshheading:16964359-Germany,
pubmed-meshheading:16964359-Humans,
pubmed-meshheading:16964359-Male,
pubmed-meshheading:16964359-Mass Screening,
pubmed-meshheading:16964359-Obesity,
pubmed-meshheading:16964359-Quantitative Trait Loci,
pubmed-meshheading:16964359-Questionnaires,
pubmed-meshheading:16964359-Risk Assessment,
pubmed-meshheading:16964359-Risk Factors,
pubmed-meshheading:16964359-Siblings,
pubmed-meshheading:16964359-Social Environment
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pubmed:year |
2006
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pubmed:articleTitle |
Practical considerations on the use of extreme sib-pairs for obesity.
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pubmed:affiliation |
Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, 23538 Lübeck, Germany. ziegler@imbs.uni-luebeck.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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