Source:http://linkedlifedata.com/resource/pubmed/id/16963683
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2006-9-11
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| pubmed:abstractText |
To determine if obesity-related changes in lung volume might contribute to airway reactivity, we investigated the effects of simulated mild obesity-related lung volume reductions on airway responsiveness in lean, nonasthmatic subjects. Participants and methods: We simulated the lung volume reductions of class 1 obesity in eight lean, nonasthmatic subjects by externally mass loading the chest wall and abdomen, and shifting blood volume into the lung with lower limb compression (LLC). Airway responsiveness was assessed by measuring FEV(1) before and after methacholine challenge tests (1, 2.5, 5, 10, and 25 mg/mL) with the following: (1) no intervention (control); (2) external chest loading (CL); (3) LLC; and (4) CL and LLC (COMB) on separate days. Lung function was measured before and after CL, LLC, and COMB were applied.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
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| pubmed:issn |
0012-3692
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
130
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
834-40
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:16963683-Administration, Inhalation,
pubmed-meshheading:16963683-Adult,
pubmed-meshheading:16963683-Asthma,
pubmed-meshheading:16963683-Bronchial Hyperreactivity,
pubmed-meshheading:16963683-Bronchial Provocation Tests,
pubmed-meshheading:16963683-Bronchoconstrictor Agents,
pubmed-meshheading:16963683-Expiratory Reserve Volume,
pubmed-meshheading:16963683-Forced Expiratory Volume,
pubmed-meshheading:16963683-Functional Residual Capacity,
pubmed-meshheading:16963683-Humans,
pubmed-meshheading:16963683-Lung,
pubmed-meshheading:16963683-Lung Volume Measurements,
pubmed-meshheading:16963683-Methacholine Chloride,
pubmed-meshheading:16963683-Models, Biological,
pubmed-meshheading:16963683-Obesity,
pubmed-meshheading:16963683-Physical Stimulation,
pubmed-meshheading:16963683-Pulmonary Ventilation,
pubmed-meshheading:16963683-Random Allocation,
pubmed-meshheading:16963683-Respiratory Function Tests
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| pubmed:year |
2006
|
| pubmed:articleTitle |
Simulated obesity-related changes in lung volume increases airway responsiveness in lean, nonasthmatic subjects.
|
| pubmed:affiliation |
School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei 100, Taiwan, ROC. liying@ntu.edu.tw
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies
|