Linked Life Data

16962181

Source:http://linkedlifedata.com/resource/pubmed/id/16962181

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-11-6
pubmed:abstractText
In a series of three experiments, simple reaction time (RT) was characterized with respect to a variable preparatory interval (PI) in order to investigate the relationship between interval timing and RT. In Experiment 1, it was shown that RT decreases as a function of PI and that this effect varies with amount of training. In Experiment 2, RT was shown to increase during probe trials that used a novel 6.25s PI, suggesting that the specific durations of the PIs encoded during initial training contribute to the PI effect on RT. In Experiment 3, 100 microg/kg i.p. of raclopride proportionally slowed RT as a function of the PI. These results are discussed within the context of neuropsychological models of interval timing and support an underlying role for cortico-striatal dopaminergic function in temporal processing and simple RT measurements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0166-4328
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
175
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
62-74
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Interaction of raclopride and preparatory interval effects on simple reaction time performance.
pubmed:affiliation
Department of Psychology and Neuroscience, Genome Sciences Research Building II, 3rd Floor, 572 Research Drive, Box 91050, Duke University, Durham, NC 27708, United States.
pubmed:publicationType
Journal Article, Comparative Study