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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2006-9-11
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pubmed:abstractText |
Gene complementation strategies are important in validating the roles of genes in specific phenotypes. Complementation systems in Helicobacter pylori include shuttle vectors, which transform H. pylori at relatively low frequencies, and chromosomally based approaches. Chromosomal complementation strategies are susceptible to polar effects and disruption of other H. pylori genes, leading to unwanted pleiotropic effects.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1083-4389
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
477-93
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pubmed:dateRevised |
2011-1-25
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pubmed:meshHeading |
pubmed-meshheading:16961811-Animals,
pubmed-meshheading:16961811-Arginase,
pubmed-meshheading:16961811-Arginine,
pubmed-meshheading:16961811-Bacterial Proteins,
pubmed-meshheading:16961811-Base Sequence,
pubmed-meshheading:16961811-Chromosomes, Bacterial,
pubmed-meshheading:16961811-Genetic Complementation Test,
pubmed-meshheading:16961811-Genetic Variation,
pubmed-meshheading:16961811-Helicobacter pylori,
pubmed-meshheading:16961811-Mice,
pubmed-meshheading:16961811-Mice, Inbred Strains,
pubmed-meshheading:16961811-Models, Genetic,
pubmed-meshheading:16961811-Molecular Sequence Data,
pubmed-meshheading:16961811-Mutation,
pubmed-meshheading:16961811-Phylogeny,
pubmed-meshheading:16961811-Transformation, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site.
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pubmed:affiliation |
Biology Department, University of South Alabama, Mobile, AL 36688, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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