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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-9-11
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pubmed:abstractText |
Protein S (PS) is an anticoagulant protein that functions as a cofactor for activated protein C (APC), and congenital PS deficiency is a well-known risk factor for the development of deep vein thrombosis (DVT). Recently, we and others identified the K196E missense mutation in the second epidermal growth factor-like domain of PS as a genetic risk factor for DVT in the Japanese population. The incidence of this mutation is high in the Japanese population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1538-7933
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2010-3
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16961608-Adult,
pubmed-meshheading:16961608-Age Factors,
pubmed-meshheading:16961608-Aged,
pubmed-meshheading:16961608-Aged, 80 and over,
pubmed-meshheading:16961608-Female,
pubmed-meshheading:16961608-Genotype,
pubmed-meshheading:16961608-Heterozygote,
pubmed-meshheading:16961608-Heterozygote Detection,
pubmed-meshheading:16961608-Humans,
pubmed-meshheading:16961608-Japan,
pubmed-meshheading:16961608-Male,
pubmed-meshheading:16961608-Middle Aged,
pubmed-meshheading:16961608-Molecular Epidemiology,
pubmed-meshheading:16961608-Mutation, Missense,
pubmed-meshheading:16961608-Protein S,
pubmed-meshheading:16961608-Sex Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Plasma protein S activity correlates with protein S genotype but is not sensitive to identify K196E mutant carriers.
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pubmed:affiliation |
Research Institute, National Cardiovascular Center, Suita, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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