rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2006-9-13
|
pubmed:abstractText |
The endogenous opioid system has been implicated in substance abuse and response to pharmacotherapies for nicotine and alcohol addiction. We examined (1) the association of the functional OPRM1 A118G variant with the relative reinforcing value of nicotine and (2) the main and interacting effects of the mu-opioid receptor antagonist naltrexone on nicotine reinforcement.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0033-3158
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
188
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
355-63
|
pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:16960700-Adaptation, Psychological,
pubmed-meshheading:16960700-Adolescent,
pubmed-meshheading:16960700-Adult,
pubmed-meshheading:16960700-Aged,
pubmed-meshheading:16960700-Double-Blind Method,
pubmed-meshheading:16960700-Female,
pubmed-meshheading:16960700-Humans,
pubmed-meshheading:16960700-Male,
pubmed-meshheading:16960700-Middle Aged,
pubmed-meshheading:16960700-Naltrexone,
pubmed-meshheading:16960700-Narcotic Antagonists,
pubmed-meshheading:16960700-Nicotine,
pubmed-meshheading:16960700-Polymorphism, Genetic,
pubmed-meshheading:16960700-Receptors, Opioid, mu,
pubmed-meshheading:16960700-Reinforcement (Psychology),
pubmed-meshheading:16960700-Risk Factors,
pubmed-meshheading:16960700-Sex Factors,
pubmed-meshheading:16960700-Smoking,
pubmed-meshheading:16960700-Smoking Cessation,
pubmed-meshheading:16960700-Substance Withdrawal Syndrome
|
pubmed:year |
2006
|
pubmed:articleTitle |
Association of OPRM1 A118G variant with the relative reinforcing value of nicotine.
|
pubmed:affiliation |
Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
|
pubmed:publicationType |
Journal Article,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|