Linked Life Data

1695695

Source:http://linkedlifedata.com/resource/pubmed/id/1695695

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-8-24
pubmed:abstractText
The relationship between the silver-stained proteins of interphase nucleolar organizer regions (NORs) and proliferative activity was studied in 12 established cell lines derived from different tumor types. Quantitative evaluation of NOR proteins was carried out on silver-stained cells, by means of an automated image analyzer and the cell proliferation rate was measured with [3H] thymidine labeling. A linear relationship was found between cell duplication activity and the amount of silver-stained NOR proteins independently of the type of cancer cells (r = 0.94, p less than 0.001). Measurement of silver-stained NOR protein could thus be used as a simple estimate of cancer cell proliferation rate.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0023-6837
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Quantity of nucleolar silver-stained proteins is related to proliferating activity in cancer cells.
pubmed:affiliation
Dipartimento di Patologia Sperimentale, Università di Bologna, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't