| pubmed-article:16956609 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C0206131 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C0163260 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C1456820 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:16956609 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:16956609 | pubmed:issue | 21 | lld:pubmed |
| pubmed-article:16956609 | pubmed:dateCreated | 2006-9-12 | lld:pubmed |
| pubmed-article:16956609 | pubmed:abstractText | The tumor necrosis factor-alpha (TNF-alpha) expression has been reported to be largely dependent on the size of adipocytes. We herein investigated the gene regulation of diacylglycerol O-acyltransferase (DGAT) in order to clarify the mechanism of TNF-alpha expression induced in large adipocytes. 3T3-L1 cells were cultured in the presence of 5 mM or 25 mM glucose to generate adipocytes from which the triglyceride content differs. The expression of TNF-alpha, DGAT1, and DGAT2 were upregulated in adipocytes cultured with 25 mM glucose. Furthermore, knockdown of DGAT1 gene significantly inhibited the TNF-alpha expression. Finally, the DGAT1 expression levels were closely related to the TNF-alpha level in 3T3-L1 adipocytes. | lld:pubmed |
| pubmed-article:16956609 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16956609 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16956609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16956609 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16956609 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16956609 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:16956609 | pubmed:author | pubmed-author:SaitoYasushiY | lld:pubmed |
| pubmed-article:16956609 | pubmed:author | pubmed-author:UnokiHiroyuki... | lld:pubmed |
| pubmed-article:16956609 | pubmed:author | pubmed-author:UenoKoichiK | lld:pubmed |
| pubmed-article:16956609 | pubmed:author | pubmed-author:BujoHideakiH | lld:pubmed |
| pubmed-article:16956609 | pubmed:author | pubmed-author:HirataTakashi... | lld:pubmed |
| pubmed-article:16956609 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16956609 | pubmed:day | 18 | lld:pubmed |
| pubmed-article:16956609 | pubmed:volume | 580 | lld:pubmed |
| pubmed-article:16956609 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16956609 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16956609 | pubmed:pagination | 5117-21 | lld:pubmed |
| pubmed-article:16956609 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:meshHeading | pubmed-meshheading:16956609... | lld:pubmed |
| pubmed-article:16956609 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16956609 | pubmed:articleTitle | Activation of diacylglycerol O-acyltransferase 1 gene results in increased tumor necrosis factor-alpha gene expression in 3T3-L1 adipocytes. | lld:pubmed |
| pubmed-article:16956609 | pubmed:affiliation | Department of Geriatric Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan. | lld:pubmed |
| pubmed-article:16956609 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16956609 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:13350 | entrezgene:pubmed | pubmed-article:16956609 | lld:entrezgene |
| entrez-gene:21926 | entrezgene:pubmed | pubmed-article:16956609 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:16956609 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:16956609 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16956609 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16956609 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16956609 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16956609 | lld:pubmed |
