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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2006-9-12
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pubmed:abstractText |
Cellular hypertrophy requires coordinated regulation of progrowth and antigrowth mechanisms. In cultured neonatal cardiomyocytes, Foxo transcription factors trigger an atrophy-related gene program that counters hypertrophic growth. However, downstream molecular events are not yet well defined.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Calcineurin,
http://linkedlifedata.com/resource/pubmed/chemical/DSCR1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Forkhead Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/FoxO3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Foxo1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Foxo1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Foxo3a protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Intracellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/MCIP-1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Muscle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NFATC Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoric Monoester Hydrolases,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/calcineurin phosphatase
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BerenjiKambeezK,
pubmed-author:CastrillonDiego HDH,
pubmed-author:ChengJunJ,
pubmed-author:DeyAsimA,
pubmed-author:GerardRobert DRD,
pubmed-author:HillJoseph AJA,
pubmed-author:LuGuangrongG,
pubmed-author:MorrisDavid JDJ,
pubmed-author:OhMisookM,
pubmed-author:RothermelBeverly ABA,
pubmed-author:SachanNitaN,
pubmed-author:WangNaN,
pubmed-author:YanesBB
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pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1159-68
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16952979-Angiotensin II,
pubmed-meshheading:16952979-Animals,
pubmed-meshheading:16952979-Calcineurin,
pubmed-meshheading:16952979-Cardiomegaly,
pubmed-meshheading:16952979-Cells, Cultured,
pubmed-meshheading:16952979-Forkhead Transcription Factors,
pubmed-meshheading:16952979-Gene Expression Regulation,
pubmed-meshheading:16952979-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:16952979-Male,
pubmed-meshheading:16952979-Mice,
pubmed-meshheading:16952979-Mice, Inbred C57BL,
pubmed-meshheading:16952979-Muscle Proteins,
pubmed-meshheading:16952979-Myocytes, Cardiac,
pubmed-meshheading:16952979-NFATC Transcription Factors,
pubmed-meshheading:16952979-Nerve Tissue Proteins,
pubmed-meshheading:16952979-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:16952979-Phosphoric Monoester Hydrolases,
pubmed-meshheading:16952979-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:16952979-Rats,
pubmed-meshheading:16952979-Rats, Sprague-Dawley,
pubmed-meshheading:16952979-Signal Transduction,
pubmed-meshheading:16952979-Transcription Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling.
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pubmed:affiliation |
Department of Internal Medicine-Cardiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8573, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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