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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-9-5
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|
pubmed:abstractText |
Loss of the basement membrane (BM) is considered an important step toward tumor malignancy. However, the BM is still expressed in most typical colorectal adenocarcinomas; nevertheless, these tumors can invade and develop metastases. The aim of this study was to investigate the role, mechanisms, and clinical relevance of BM turnover in malignant colorectal cancer (CRC) progression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
Sep
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|
pubmed:issn |
0016-5085
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
131
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
830-40
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|
pubmed:dateRevised |
2007-5-22
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pubmed:meshHeading |
pubmed-meshheading:16952552-Adenocarcinoma,
pubmed-meshheading:16952552-Adult,
pubmed-meshheading:16952552-Aged,
pubmed-meshheading:16952552-Aged, 80 and over,
pubmed-meshheading:16952552-Basement Membrane,
pubmed-meshheading:16952552-Cell Line, Tumor,
pubmed-meshheading:16952552-Colorectal Neoplasms,
pubmed-meshheading:16952552-DNA, Neoplasm,
pubmed-meshheading:16952552-Down-Regulation,
pubmed-meshheading:16952552-Female,
pubmed-meshheading:16952552-Follow-Up Studies,
pubmed-meshheading:16952552-Homeodomain Proteins,
pubmed-meshheading:16952552-Humans,
pubmed-meshheading:16952552-Immunohistochemistry,
pubmed-meshheading:16952552-Male,
pubmed-meshheading:16952552-Middle Aged,
pubmed-meshheading:16952552-Survival Rate,
pubmed-meshheading:16952552-Transcription Factors
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pubmed:year |
2006
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|
pubmed:articleTitle |
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer.
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pubmed:affiliation |
Department of Pathology, University of Erlangen-Nürnberg, Erlangen, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't
|
