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rdf:type |
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lifeskim:mentions |
umls-concept:C0021311,
umls-concept:C0021853,
umls-concept:C0024264,
umls-concept:C0024501,
umls-concept:C0205266,
umls-concept:C0221908,
umls-concept:C0242358,
umls-concept:C0721534,
umls-concept:C0871261,
umls-concept:C1512942,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
3
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pubmed:dateCreated |
2006-9-5
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pubmed:abstractText |
Intestinal epithelial integrity and permeability is dependent on intercellular tight junction (TJ) complexes. How TJ integrity is regulated remains unclear, although phosphorylation and dephosphorylation of the integral membrane protein occludin is an important determinant of TJ formation and epithelial permeability. We have investigated the role intestinal intraepithelial lymphocytes (iIELs) play in regulating epithelial permeability in response to infection.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:AndrewElizabeth MEM,
pubmed-author:CardingSimon RSR,
pubmed-author:CruickshankSheena MSM,
pubmed-author:DaltonJane EJE,
pubmed-author:EganCharlotte ECE,
pubmed-author:ElseKathryn JKJ,
pubmed-author:GubbelsMarc-JanMJ,
pubmed-author:HowellGarethG,
pubmed-author:LawrenceBethB,
pubmed-author:MearsRainyR,
pubmed-author:NewtonDarren JDJ,
pubmed-author:SmithJudith EJE,
pubmed-author:StriepenBorisB,
pubmed-author:WhiteStanley JSJ
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pubmed:issnType |
Print
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
818-29
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pubmed:dateRevised |
2007-8-13
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pubmed:meshHeading |
pubmed-meshheading:16952551-Animals,
pubmed-meshheading:16952551-Blotting, Western,
pubmed-meshheading:16952551-Cell Membrane Permeability,
pubmed-meshheading:16952551-Disease Models, Animal,
pubmed-meshheading:16952551-Immunohistochemistry,
pubmed-meshheading:16952551-Immunoprecipitation,
pubmed-meshheading:16952551-Intercellular Junctions,
pubmed-meshheading:16952551-Intestinal Mucosa,
pubmed-meshheading:16952551-Male,
pubmed-meshheading:16952551-Membrane Proteins,
pubmed-meshheading:16952551-Mice,
pubmed-meshheading:16952551-Mice, Inbred C57BL,
pubmed-meshheading:16952551-Phosphorylation,
pubmed-meshheading:16952551-RNA,
pubmed-meshheading:16952551-Receptors, Antigen, T-Cell, gamma-delta,
pubmed-meshheading:16952551-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16952551-T-Lymphocytes,
pubmed-meshheading:16952551-Toxoplasma,
pubmed-meshheading:16952551-Toxoplasmosis, Animal
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pubmed:year |
2006
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pubmed:articleTitle |
Intraepithelial gammadelta+ lymphocytes maintain the integrity of intestinal epithelial tight junctions in response to infection.
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pubmed:affiliation |
Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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