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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-1-15
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pubmed:abstractText |
"Atypical anti-psychotics" are substances of choice in treating drug-induced psychosis (DP) in Parkinson's disease (PD). We report on four patients with DP who received treatment with ziprasidone after previously applied clozapine and quetiapine had failed. Three patients showed a significant improvement of DP, without deterioration of motor function. In one case, ziprasidone considerably increased decline in off-periods. Two patients developed pathological laughing as a possible side-effect of ziprasidone. Ziprasidone may serve as an additional "atypical anti-psychotic" for the treatment of DP in PD but can also induce deterioration of motor function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0303-8467
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
188-91
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pubmed:dateRevised |
2009-10-14
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pubmed:meshHeading |
pubmed-meshheading:16949733-Aged,
pubmed-meshheading:16949733-Antiparkinson Agents,
pubmed-meshheading:16949733-Antipsychotic Agents,
pubmed-meshheading:16949733-Clozapine,
pubmed-meshheading:16949733-Dibenzothiazepines,
pubmed-meshheading:16949733-Dose-Response Relationship, Drug,
pubmed-meshheading:16949733-Drug Therapy, Combination,
pubmed-meshheading:16949733-Humans,
pubmed-meshheading:16949733-Laughter,
pubmed-meshheading:16949733-Levodopa,
pubmed-meshheading:16949733-Male,
pubmed-meshheading:16949733-Middle Aged,
pubmed-meshheading:16949733-Neurologic Examination,
pubmed-meshheading:16949733-Parkinson Disease,
pubmed-meshheading:16949733-Parkinson Disease, Secondary,
pubmed-meshheading:16949733-Piperazines,
pubmed-meshheading:16949733-Psychoses, Substance-Induced,
pubmed-meshheading:16949733-Thiazoles
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pubmed:year |
2007
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pubmed:articleTitle |
Treatment of drug-induced psychosis in Parkinson's disease with ziprasidone can induce severe dose-dependent off-periods and pathological laughing.
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pubmed:affiliation |
Paracelsus Elena-Klinik Kassel, Klinikstrasse 16, 34128 Kassel, Germany. jschind@gwdg.de
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pubmed:publicationType |
Journal Article,
Case Reports
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