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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
14
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pubmed:dateCreated |
1990-8-8
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pubmed:abstractText |
Two T-cell lines (XR11-4T and XR11-5T), established from radiation-induced, murine lymphoblastic lymphomas, were examined for the expression of class I major histocompatibility complex antigen and tumor induction. These cell lines expressed class I private determinants, H-2.9 and H-2.26, but not the monomorphic determinant defined by monoclonal antibody M1/42. Both cell lines produced tumors in syngeneic and allogeneic hosts. The monomorphic determinant could be demonstrated on both cell lines following growth in allogeneic (BALB/c mice) but not in syngeneic (RFM mice) hosts. The re-expressed determinant present on cells following growth in allogeneic mice was not of host origin. Thus, tumorigenic x irradiation may differentially affect the expression of class I major histocompatibility complex determinants.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0027-8874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1209-14
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1694547-Animals,
pubmed-meshheading:1694547-Epitopes,
pubmed-meshheading:1694547-Genes, MHC Class I,
pubmed-meshheading:1694547-Leukemia, Lymphoid,
pubmed-meshheading:1694547-Leukemia, Radiation-Induced,
pubmed-meshheading:1694547-Lymphoma, Non-Hodgkin,
pubmed-meshheading:1694547-Mice,
pubmed-meshheading:1694547-Mice, Inbred BALB C,
pubmed-meshheading:1694547-Mice, Inbred Strains,
pubmed-meshheading:1694547-Neoplasm Transplantation,
pubmed-meshheading:1694547-Transplantation Immunology,
pubmed-meshheading:1694547-Tumor Cells, Cultured
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pubmed:year |
1990
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pubmed:articleTitle |
Differential expression of class I major histocompatibility complex determinants by lymphoblastic leukemia-lymphoma cell lines.
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pubmed:affiliation |
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile 36688.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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