Linked Life Data

16944418

Source:http://linkedlifedata.com/resource/pubmed/id/16944418

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-8-31
pubmed:abstractText
Oocytes from virtually all organisms are surrounded by at least one coat. This specialized extracellular matrix, called the zona pellucida (ZP) in mammals and the vitelline envelope (VE) in nonmammals, has a structural function and plays essential roles in oogenesis, fertilization, and early development. During the last 15 years, compelling evidence has accumulated that all ZP/VE subunits polymerize using a conserved sequence, the ZP domain, so that the basic structural features of egg coat matrices have been maintained through evolution. Moreover, ZP domains have been identified in many other polymeric extracellular proteins from eukaryotes. This review compares the ultrastructure and molecular composition of egg coats from mollusc to human, suggests a common mechanism for assembly of ZP/VE proteins, and discusses alternative models of how these could be arranged within filaments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1526-8004
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
204-16
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Tracking down the ZP domain: From the mammalian zona pellucida to the molluscan vitelline envelope.
pubmed:affiliation
Karolinska Institutet, Department of Biosciences and Nutrition, Center for Structural Biochemistry, Huddinge, Sweden.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't