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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-11-14
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pubmed:abstractText |
We studied POLG1 in 140 UK patients with idiopathic Parkinson disease (PD) and 279 Italian patients with PD and compared them to a UK control group (n = 207) and an Italian control group (n = 285). Our observations do not support a role for common POLG1 genetic variants in PD and indicate that dominant POLG1 mutations are a rare cause of parkinsonism in the general population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1698-700
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16943369-Aged,
pubmed-meshheading:16943369-Cohort Studies,
pubmed-meshheading:16943369-DNA Mutational Analysis,
pubmed-meshheading:16943369-DNA-Directed DNA Polymerase,
pubmed-meshheading:16943369-Exons,
pubmed-meshheading:16943369-Female,
pubmed-meshheading:16943369-Gene Frequency,
pubmed-meshheading:16943369-Genetic Markers,
pubmed-meshheading:16943369-Genetic Predisposition to Disease,
pubmed-meshheading:16943369-Genetic Testing,
pubmed-meshheading:16943369-Genetic Variation,
pubmed-meshheading:16943369-Genotype,
pubmed-meshheading:16943369-Great Britain,
pubmed-meshheading:16943369-Humans,
pubmed-meshheading:16943369-Italy,
pubmed-meshheading:16943369-Male,
pubmed-meshheading:16943369-Middle Aged,
pubmed-meshheading:16943369-Mutation,
pubmed-meshheading:16943369-Parkinson Disease,
pubmed-meshheading:16943369-Polymorphism, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
POLG1 in idiopathic Parkinson disease.
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pubmed:affiliation |
Department of Neurology, University of Newcastle upon Tyne, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
