Linked Life Data

16943021

Source:http://linkedlifedata.com/resource/pubmed/id/16943021

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-8-31
pubmed:abstractText
Jenseniin G is an antibotulinal bacteriocin (antimicrobial peptide) produced by the dairy culture, Propionibacterium thoenii (jensenii) P126. Activity from crude jenseniin G preparations isolated from static cultures was not detected in unconcentrated cultures before day 7. Activity was not detectable until the spent culture medium was concentrated 50-100 fold. Maximum activity (21 AU/ml) was observed in concentrated supernates at day 9. The production of bacteriocin jenseniin G was increased in fed-batch fermentations for 14 d at 32 degrees C in sodium lactate broth (NLB) containing 1.2% sodium lactate. Viable cell numbers in static and fed-batch cultures reached 1.2 and 5.4x10(9), respectively, during late exponential/early stationary phase (3 d). Concentrations of viable cells in fed-batch fermentations remained constant throughout the incubation period; those in static fermentations dropped after day 6 to a final concentration of 1.5x10(7). During fed-batch fermentations, jenseniin G was directly detected at day 5. In fed-batch fermentations, maximum activity in concentrated supernates (384 AU/ml) on day 12 provided an 18 fold increase over yields in static cultures and in fermenter without pH control, and 2.4 fold increase over yields in fermenter at controlled pH at 6.4. Fed-batch fermentation shows promise as a method to obtain high concentrations of industrially significant bacteriocins from dairy propionibacteria.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0740-0020
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-30
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Fed-batch enhancement of jenseniin G, a bacteriocin produced by Propionibacterium thoenii (jensenii) P126.
pubmed:affiliation
Clemson University, Clemson, South Carolina 29634-0371, USA. yekinci@ziraat.sdu.edu.tr
pubmed:publicationType
Journal Article