Source:http://linkedlifedata.com/resource/pubmed/id/16940741
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-10-18
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pubmed:abstractText |
A 43-year-old man developed a skin eruption characterized by 'macules with blisters' typical to Stevens-Johnson syndrome, as well as erosions of the lips and buccal mucosa, 2 weeks after he had started treatment with lamotrigine. He had a fever (39.6 degrees C), elevated liver enzymes and atypical lymphocytes in the peripheral blood. This undoubtedly reflects a case of Stevens-Johnson syndrome induced by lamotrigine, but it can also fulfill the criteria of anticonvulsant hypersensitivity syndrome or drug rash with eosinophilia and systemic signs. A case that precisely fits the definition of two syndromes that have different characteristics, different treatments and different prognoses indicates that there is a flaw in the classification.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1018-2438
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
308-10
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pubmed:meshHeading |
pubmed-meshheading:16940741-Adult,
pubmed-meshheading:16940741-Diagnosis, Differential,
pubmed-meshheading:16940741-Drug Eruptions,
pubmed-meshheading:16940741-Eosinophilia,
pubmed-meshheading:16940741-Humans,
pubmed-meshheading:16940741-Male,
pubmed-meshheading:16940741-Stevens-Johnson Syndrome,
pubmed-meshheading:16940741-Systemic Inflammatory Response Syndrome,
pubmed-meshheading:16940741-Triazines
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pubmed:year |
2006
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pubmed:articleTitle |
Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome--a case that indicates a stumbling block in the current classification.
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pubmed:affiliation |
Dermatology Unit, Kaplan Medical Center, Rechovot, Israel. wolf_r@netvision.net.il
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pubmed:publicationType |
Journal Article,
Case Reports
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