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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1473
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pubmed:dateCreated |
2006-8-30
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pubmed:abstractText |
This paper emphasizes several characteristics of the neural control of locomotion that provide opportunities for developing strategies to maximize the recovery of postural and locomotor functions after a spinal cord injury (SCI). The major points of this paper are: (i) the circuitry that controls standing and stepping is extremely malleable and reflects a continuously varying combination of neurons that are activated when executing stereotypical movements; (ii) the connectivity between neurons is more accurately perceived as a functional rather than as an anatomical phenomenon; (iii) the functional connectivity that controls standing and stepping reflects the physiological state of a given assembly of synapses, where the probability of these synaptic events is not deterministic; (iv) rather, this probability can be modulated by other factors such as pharmacological agents, epidural stimulation and/or motor training; (v) the variability observed in the kinematics of consecutive steps reflects a fundamental feature of the neural control system and (vi) machine-learning theories elucidate the need to accommodate variability in developing strategies designed to enhance motor performance by motor training using robotic devices after an SCI.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-10400964,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-10635715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-10740227,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-11240278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-11283749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-11351008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-11784280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-11918656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-11943816,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12193190,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12440356,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12440362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12440365,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12440370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12440372,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12589916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12589925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-126163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12684465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12762591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-12838332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-134622,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14624080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14653157,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14653171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14668296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14762160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14987469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-14988161,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15011268,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15055447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15101086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15217329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15647397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15872066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15875491,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-15878636,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-1588602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-16049043,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-184256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-2336984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-2357538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-2675307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-3607464,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-3709720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-3709721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-3956672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-4966862,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-6000625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-7620630,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-7888773,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-8270914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-8993704,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9464971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9497414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9535975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9658030,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9674553,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9751133,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16939979-9928325
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0962-8436
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
361
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1635-46
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2006
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pubmed:articleTitle |
Plasticity of functional connectivity in the adult spinal cord.
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pubmed:affiliation |
Bioengineering Option, California Institute of Technology, Pasadena, CA 91125-4100, USA.
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pubmed:publicationType |
Journal Article,
Review
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