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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-8-30
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pubmed:abstractText |
Osteoclastic bone degradation involves the activity of cathepsin K. We found that in addition to this enzyme other, yet unknown, cysteine proteinases participate in digestion. The results support the notion that osteoclasts from different bone sites use different enzymes to degrade the collagenous bone matrix.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cathepsin K,
http://linkedlifedata.com/resource/pubmed/chemical/Cathepsin L,
http://linkedlifedata.com/resource/pubmed/chemical/Cathepsins,
http://linkedlifedata.com/resource/pubmed/chemical/Ctsk protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Ctsl protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine Proteinase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Extracts
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0884-0431
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pubmed:author |
pubmed-author:BeertsenWouterW,
pubmed-author:BrommeDieterD,
pubmed-author:CleutjensKitty B J MKB,
pubmed-author:EvertsVincentV,
pubmed-author:HeenemanSylviaS,
pubmed-author:HoebenKees AKA,
pubmed-author:JansenIneke D CID,
pubmed-author:KorperWolfW,
pubmed-author:PetersChristophC,
pubmed-author:ReinheckelThomasT,
pubmed-author:SaftigPaulP
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1399-408
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16939398-Animals,
pubmed-meshheading:16939398-Bone Resorption,
pubmed-meshheading:16939398-Bone and Bones,
pubmed-meshheading:16939398-Cathepsin K,
pubmed-meshheading:16939398-Cathepsin L,
pubmed-meshheading:16939398-Cathepsins,
pubmed-meshheading:16939398-Cysteine Endopeptidases,
pubmed-meshheading:16939398-Cysteine Proteinase Inhibitors,
pubmed-meshheading:16939398-Humerus,
pubmed-meshheading:16939398-Matrix Metalloproteinases,
pubmed-meshheading:16939398-Metacarpal Bones,
pubmed-meshheading:16939398-Mice,
pubmed-meshheading:16939398-Mice, Inbred C57BL,
pubmed-meshheading:16939398-Mice, Knockout,
pubmed-meshheading:16939398-Skull,
pubmed-meshheading:16939398-Tissue Culture Techniques,
pubmed-meshheading:16939398-Tissue Extracts
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pubmed:year |
2006
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pubmed:articleTitle |
Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone.
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pubmed:affiliation |
Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam, Amsterdam, The Netherlands. v.everts@vumc.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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