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16934456
Source:
http://linkedlifedata.com/resource/pubmed/id/16934456
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rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0243076
,
umls-concept:C0524914
,
umls-concept:C1334125
,
umls-concept:C1334126
pubmed:issue
21
pubmed:dateCreated
2006-9-25
pubmed:abstractText
A series of N-(2-hydroxy-3-sulfonamidobenzene)-N'-arylcyanoguanidines was prepared. In general, these compounds proved to be potent antagonists of CXCR2 while the selectivity versus CXCR1 ranged from non-selective to >200-fold.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Guanidines
,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-8A
,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-8B
,
http://linkedlifedata.com/resource/pubmed/chemical/dicyandiamido
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0960-894X
pubmed:author
pubmed-author:BryanDeborah LDL
,
pubmed-author:BurmanMiriamM
,
pubmed-author:Busch-PetersenJakobJ
,
pubmed-author:ElliottJohn DJD
,
pubmed-author:FoleyJames JJJ
,
pubmed-author:LiY PYP
,
pubmed-author:NieHongH
,
pubmed-author:PalovichMichael RMR
,
pubmed-author:SarauHenry MHM
,
pubmed-author:SchmidtDulcie BDB
,
pubmed-author:WiddowsonKatherine LKL
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5513-6
pubmed:meshHeading
pubmed-meshheading:16934456-Guanidines
,
pubmed-meshheading:16934456-Humans
,
pubmed-meshheading:16934456-Receptors, Interleukin-8A
,
pubmed-meshheading:16934456-Receptors, Interleukin-8B
pubmed:year
2006
pubmed:articleTitle
N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors.
pubmed:affiliation
GlaxoSmithKline, 709 Swedeland Road, King of Prussia, PA 19406, USA.
pubmed:publicationType
Journal Article