Linked Life Data

16934375

Source:http://linkedlifedata.com/resource/pubmed/id/16934375

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
40-41
pubmed:dateCreated
2006-9-11
pubmed:abstractText
The comparative efficacy and safety of measles vaccination via the aerosol route versus subcutaneous injection has not been fully resolved. We vaccinated cynomolgus monkeys (Macaca fascicularis) with the live-attenuated Edmonston-Zagreb measles virus (MV) vaccine and compared different routes of administration in the immunocompetent and the immunocompromised host. Immunogenicity and protective efficacy of aerosol vaccination using devices similar to those previously used in humans were comparable to those in animals vaccinated by injection. No evidence for a safety hazard associated with the route of vaccination was detected. The results of this study support further clinical evaluation of aerosol vaccination for measles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0264-410X
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6424-36
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Aerosol measles vaccination in macaques: preclinical studies of immune responses and safety.
pubmed:affiliation
Department of Virology, Erasmus MC, Postgraduate School of Molecular Medicine, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands. r.deswart@erasmusmc.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't