pubmed:abstractText |
Anastrozole and tamoxifen have mild toxicity. However, we noticed that more patients treated with anastrozole complained of joint symptoms than expected. In particular, digital stiffness as is seen with rheumatoid arthritis is a problem. Some clinical trials of anastrozole in Europe and the United States reported musculoskeletal disorders as adverse events, however, joint symptoms were not described in detail.
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pubmed:affiliation |
Department of Surgery, Japan Labour Health and Welfare Organization-Kumamoto Rosai Hospital, 167 Takehara-cho, Yatsushiro-city, Kumamoto 866-8533, Japan. geka-ohsako@kumamotoh.rofuku.go.jp
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