Source:http://linkedlifedata.com/resource/pubmed/id/16928972
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-9-22
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pubmed:abstractText |
Permission from the ethics committee and informed consent were obtained. The purpose of this study was to prospectively evaluate a method developed for the noninvasive assessment of muscle metabolites during exercise. Hydrogen 1 magnetic resonance (MR) spectroscopy peaks were measured during tetanic isometric muscle contraction imposed by supramaximal repetitive nerve stimulation. The kinetics of creatine-phosphocreatine and acetylcarnitine signal changes (P < .001) could be assessed continuously before, during, and after exercise. The control peak (trimethylammonium compounds), which served as an internal reference, did not change. This technique-that is, functional MR spectroscopy-opens the possibility for noninvasive diagnostic muscle metabolite testing in a clinical setting.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:copyrightInfo |
(c) RSNA, 2006.
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pubmed:issnType |
Print
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pubmed:volume |
241
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
235-42
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pubmed:meshHeading |
pubmed-meshheading:16928972-Acetylcarnitine,
pubmed-meshheading:16928972-Adult,
pubmed-meshheading:16928972-Creatine,
pubmed-meshheading:16928972-Electric Stimulation,
pubmed-meshheading:16928972-Exercise,
pubmed-meshheading:16928972-Humans,
pubmed-meshheading:16928972-Magnetic Resonance Spectroscopy,
pubmed-meshheading:16928972-Male,
pubmed-meshheading:16928972-Middle Aged,
pubmed-meshheading:16928972-Muscle Contraction,
pubmed-meshheading:16928972-Muscles,
pubmed-meshheading:16928972-Phosphocreatine,
pubmed-meshheading:16928972-Prospective Studies
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pubmed:year |
2006
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pubmed:articleTitle |
Muscle metabolites: functional MR spectroscopy during exercise imposed by tetanic electrical nerve stimulation.
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pubmed:affiliation |
Department of Neurology, University Hospital, Inselspital, CH-3010 Bern, Switzerland. anirkko@insel.ch
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pubmed:publicationType |
Journal Article
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