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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-9-5
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pubmed:abstractText |
alpha-E-catenin is a cell adhesion protein, located within the adherens junction, thought to be essential in directly linking the cadherin-based adhesion complex to the actin cytoskeleton. Although alpha-E-catenin is expressed in the adherens junction of the cardiomyocyte intercalated disc, and perturbations in its expression are observed in models of dilated cardiomyopathy, its role in the myocardium remains unknown.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:ChenJuJ,
pubmed-author:ChenYinghongY,
pubmed-author:ChenYinhongY,
pubmed-author:DaltonNancy DND,
pubmed-author:GuYusuY,
pubmed-author:HirschyAlainA,
pubmed-author:KnowltonKirk UKU,
pubmed-author:LiangXingqunX,
pubmed-author:LuYingchunY,
pubmed-author:PerriardJean-ClaudeJC,
pubmed-author:PetersonKirk LKL,
pubmed-author:SheikhFarahF,
pubmed-author:StenbitAntine EAE,
pubmed-author:YajimaToshitakaT
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pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1046-55
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pubmed:dateRevised |
2007-1-24
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pubmed:meshHeading |
pubmed-meshheading:16923756-Animals,
pubmed-meshheading:16923756-Cardiomyopathy, Dilated,
pubmed-meshheading:16923756-Disease Models, Animal,
pubmed-meshheading:16923756-Electrocardiography,
pubmed-meshheading:16923756-Mice,
pubmed-meshheading:16923756-Mice, Knockout,
pubmed-meshheading:16923756-Muscle Cells,
pubmed-meshheading:16923756-Myocardial Infarction,
pubmed-meshheading:16923756-Myocardium,
pubmed-meshheading:16923756-Proteins,
pubmed-meshheading:16923756-Ventricular Dysfunction, Right,
pubmed-meshheading:16923756-alpha Catenin
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pubmed:year |
2006
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pubmed:articleTitle |
alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture.
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pubmed:affiliation |
Department of Medicine, University of California-San Diego, La Jolla, CA 92093-0613, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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