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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2006-9-19
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pubmed:abstractText |
Many vascular diseases are associated with reduced nitric oxide (NO) bioavailability. Nitric oxide synthase (NOS) gene therapy to the vasculature is a possible treatment for vascular disease as a means of increasing NO bioavailability, and this may be achieved using any of the NOS isoforms. The aim of our study was to compare the effects of adenoviral-mediated overexpression of the most commonly used NOS isoforms eNOS and iNOS on vascular cell proliferation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1018-1172
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2006 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
462-72
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16921253-Adenoviridae,
pubmed-meshheading:16921253-Angiogenesis Inhibitors,
pubmed-meshheading:16921253-Animals,
pubmed-meshheading:16921253-Cattle,
pubmed-meshheading:16921253-Cell Culture Techniques,
pubmed-meshheading:16921253-Cell Division,
pubmed-meshheading:16921253-Cloning, Organism,
pubmed-meshheading:16921253-Coronary Vessels,
pubmed-meshheading:16921253-Cytomegalovirus,
pubmed-meshheading:16921253-Gene Transfer Techniques,
pubmed-meshheading:16921253-Genetic Vectors,
pubmed-meshheading:16921253-Humans,
pubmed-meshheading:16921253-Muscle, Smooth, Vascular,
pubmed-meshheading:16921253-Nitric Oxide,
pubmed-meshheading:16921253-Nitric Oxide Synthase Type II,
pubmed-meshheading:16921253-Nitric Oxide Synthase Type III,
pubmed-meshheading:16921253-Promoter Regions, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
Adenoviral-mediated gene transfer of nitric oxide synthase isoforms and vascular cell proliferation.
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pubmed:affiliation |
Regenerative Medicine Institute (REMEDI), National Centre for Biomedical Engineering Sciences (NCBES), National University of Ireland, Galway, Ireland. timothy.obrien@nuigalway.ie
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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