Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2006-9-5
pubmed:abstractText
Conditions predisposing to metabolic syndrome (MetS) are associated with increased oxidative stress and inflammation. We studied, in vegetarians (n = 90) and omnivores (n = 46), the impact of the dietary regimen on the occurrence of MetS risk factors (RFs: BMI, blood pressure, glucose metabolism and lipid profile) in relation to oxidative status (advanced glycation end products (AGEs), advanced oxidation protein products (AOPPs), malondialdehyde, ferric reducing ability of plasma, vitamins A, E, C, beta-carotene and superoxide dismutase activity) and microinflammation (C-reactive protein, leukocytes and neopterin). The proportion of subjects without/positive for one or two MetS RFs was comparable between the groups. From the components of MetS only immunoreactive insulin levels differed significantly (95% CI: omnivores: 5.0-7.1 microU/mL, vegetarians: 4.5-5.4, p = 0.03). Omnivores had lower AOPP (omnivores: 0.29-0.36 micromol/g albumin, vegetarians: 0.36-0.52, p = 0.01) and beta-carotene levels than vegetarians, they consumed more calories, proteins, fat and saturated fatty acids, and less fibres, beta-carotene and vitamin C. Multiple regression analysis revealed vitamin E and AOPP levels as the most important independent determinants of MetS RFs. The vegetarian diet seems to exert beneficial effects on MetS RFs associated microinflammation. Whether the vegetarian diet may counteract the deleterious effects of elevated AOPPs and AGEs, remains to be elucidated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1613-4125
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
858-68
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:16917805-Antioxidants, pubmed-meshheading:16917805-Biological Markers, pubmed-meshheading:16917805-Blood Pressure, pubmed-meshheading:16917805-Blood Proteins, pubmed-meshheading:16917805-Body Mass Index, pubmed-meshheading:16917805-Diet, pubmed-meshheading:16917805-Diet, Vegetarian, pubmed-meshheading:16917805-Energy Intake, pubmed-meshheading:16917805-Glycosylation End Products, Advanced, pubmed-meshheading:16917805-Inflammation, pubmed-meshheading:16917805-Insulin, pubmed-meshheading:16917805-Insulin Resistance, pubmed-meshheading:16917805-Leukocyte Count, pubmed-meshheading:16917805-Lipid Peroxidation, pubmed-meshheading:16917805-Lipids, pubmed-meshheading:16917805-Metabolic Syndrome X, pubmed-meshheading:16917805-Neopterin, pubmed-meshheading:16917805-Oxidation-Reduction, pubmed-meshheading:16917805-Oxidative Stress, pubmed-meshheading:16917805-Risk Factors, pubmed-meshheading:16917805-Serum Albumin
pubmed:year
2006
pubmed:articleTitle
Association of metabolic syndrome risk factors with selected markers of oxidative status and microinflammation in healthy omnivores and vegetarians.
pubmed:affiliation
Research Base of Slovak Medical University, Bratislava, Slovakia. katarina.sebekova@szu.sk
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't